Paraquat: A fatal poison

Manifestation and Management of Paraquat Intoxiction. A deadly poison?

Paraquat is a bipyridilium herbicide, is a bright green corrosive liquid with pungent smell that needs to be diluted before agricultural use. Globally it is the second highest-selling weed killer used and is available in a 20% solution form.[1] Its herbicidal properties were discovered in 1950s and first marketed in 1962. Most cases of intoxication especially in third-world countries are due to...

Paraquat poisoning is not always fatal.

Of the nineteen cases of Gramoxone poisoning treated at the Medical Unit, Toa Payoh Hospital, three survived. The clinical data of these survivors is presented. The maximal ingested dose compatible with life in the present series is twenty millilitresof Grammoxonewhile the excretion rate of paraquat in urine in a non -fatal case is 0.92 mg/hr in the first 24 hours. In the follow-up of these sur...

A fatal case of paraquat poisoning following minimal dermal exposure.

Paraquat is a pesticide widely used in agriculture. Numerous cases of paraquat intoxication have been reported either accidentally or intentionally as a suicidal attempt. The most severe cases of paraquat poisoning refer to oral ingestion. Complications include respiratory, hepatic, and renal failure, and are usually fatal. Dermal exposure is less frequent and rarely fatal. This article reports...

Non-fatal lung disease due to inhalation of nebulised paraquat.

A case of fatal paraquat poisoning and a rapid method for analysis of paraquat in biological material.

In a case of fatal paraquat poisoning, the distribution of paraquat was determined by a) the column chromatographic method developed by Tompsett, b) the ion-pairing method, c) the deproteinization method both developed by Jarvie et al, and d) the precipitation method developed by the authors. The precipitation method relies on the use of a precipitate of paraquat with Reinecke's salt to extract...